Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AOM14781.1Restriction endonuclease subunit S; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)    
Predicted Functional Partners:
HsdM
Restriction endonuclease subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
hsdR_2
Deoxyribonuclease; Subunit R is required for both nuclease and ATPase activities, but not for modification.
  
 0.988
rlmL
RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methyltransferase superfamily.
      
 0.758
AOM14783.1
Type II restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.535
AOM14784.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.535
AOM16251.1
Phage antirepressor; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.523
atpF_1
ATP synthase F0F1 subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
   
 
 0.426
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.419
xerC_2
Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family.
 
  
 0.414
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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