close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOM14847.1Phosphosugar isomerase; Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid. (321 aa)    
Predicted Functional Partners:
AOM14835.1
Ribokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.891
AOM14848.1
PTS mannose transporter subunit IID; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.831
AOM14849.1
PTS mannose transporter subunit IICD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.809
AOM14851.1
PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.746
AOM14850.1
PTS mannose transporter subunit IIAB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.739
glmS_5
Glucosamine-fructose-6-phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.719
AOM14846.1
Transcription antiterminator BglG; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.716
manX
PTS mannose transporter subunit IIAB; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.527
AOM14845.1
Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.505
glmS
Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
 
  
 0.505
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.