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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RepAReplication protein RepA; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)    
Predicted Functional Partners:
AOM17128.1
Relaxase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.849
AOM14976.1
Pin-related site-specific recombinase/DNA invertase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.794
rep_1
Replication protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.769
bin3_2-2
Resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.741
AOM17615.1
Replication protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.721
hin
Resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.708
bin3_2
Resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.681
AOM15021.1
Resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.681
AOM16714.1
Resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.681
AOM14856.1
Conjugal transfer protein TraG; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.602
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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