Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RepAReplication protein RepA; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)    
Predicted Functional Partners:
AOM17128.1
Relaxase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.872
rep_1
Replication protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.803
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
   
 
 0.668
relE
Addiction module toxin RelE; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.657
AOM14856.1
Conjugal transfer protein TraG; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.634
parB
Chromosome partitioning protein ParB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ParB family.
     
 0.609
RepB2
Cobyrinic acid a,c-diamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.604
AOM14953.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.539
tnp
Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.460
ndoA
PemK family transcriptional regulator; Toxic component of a type II toxin-antitoxin (TA) system.
     
 0.460
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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