Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
bin3_2-2Resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)    
Predicted Functional Partners:
hin
Resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.775
YneF
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.676
AOM16251.1
Phage antirepressor; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.668
AOM15360.1
HNH endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.650
McrA
HNH endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.620
AOM14896.1
Addiction module protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.594
AOM16804.1
Addiction module protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.594
TelA
Tellurite resistance protein TelA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TelA family.
      
 0.590
nfo_2
Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
   
  
 0.498
traL
Sodium ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.460
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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