close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hxlB_66-phospho 3-hexuloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)    
Predicted Functional Partners:
ulaD
Catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.929
rpe
Catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family.
  
  
 0.830
AOM15004.1
Secondary thiamine-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.788
AOM15003.1
PTS galactitol transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.772
AOM15002.1
PTS galactitol transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.647
AOM15000.1
Transcriptional antiterminator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.629
AOM15001.1
PTS sugar transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.629
AOM14835.1
Ribokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.461
Tal
Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.443
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
    0.429
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.