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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOM15015.1LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)    
Predicted Functional Partners:
AOM15014.1
Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
 
  
 0.895
AOM14767.1
AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.772
ccpA_1
LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.768
AOM14799.1
LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.753
AOM15013.1
PTS sucrose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.720
ptsH
Phosphocarrier protein HPr; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.496
pyk
Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.486
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
   0.410
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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