Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AOM15024.1Sugar permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)    
Predicted Functional Partners:
NagE
PTS acetylglucosamine transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.985
AOM14749.1
PTS glucose transporter subunit IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.983
AOM16711.1
PTS glucose transporter subunit IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.983
BglPA
PTS sucrose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.955
ptsP
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
   
 0.924
AOM14739.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
      0.675
murQ
N-acetylmuramic acid-6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.
     
 0.623
BglP2
PTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.501
AOM15013.1
PTS sucrose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.489
AOM14811.1
Sucrose-6-phosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.483
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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