Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
icaRTetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)    
Predicted Functional Partners:
AOM15090.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.786
lolD_2
Hemin ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.752
AOM17238.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.571
marR
MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.539
AOM17159.1
NAD(P)H nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.519
AOM15887.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.481
ywnA
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.481
MarR
MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.477
AOM15493.1
Nucleic acid-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.467
AOM15088.1
M protein trans-acting positive regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.438
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.