Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cwlCCell wall hydrolase; Probably involved in cell-wall metabolism. Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family. (303 aa)    
Predicted Functional Partners:
gluP
Peptidase S54; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.721
murI_1
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
  
  
 0.707
pknB
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.698
AmiC
N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.686
SagA
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.671
AOM17095.1
N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.658
yfaY
Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
 
   
 0.651
hisS
histidyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.641
cca
tRNA CCA-pyrophosphorylase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
  
 
 0.634
AOM16683.1
Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.631
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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