Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ywiBHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)    
Predicted Functional Partners:
AOM15119.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.911
lipL
Lipoate--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.881
yidA_3
Sugar phosphatase; YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.828
rpoE
DNA-directed RNA polymerase subunit delta; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family.
 
    0.828
AOM16395.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.825
AOM17408.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.714
AOM15588.1
Peptidoglycan-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.697
argS_1
arginine--tRNA ligase; Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.695
GtrA
Teichoic acid glycosylation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.667
yhhT_3
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.642
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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