Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sigVRNA polymerase subunit sigma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (168 aa)    
Predicted Functional Partners:
rsiV
Anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.875
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.795
PgdA
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.788
rpoN
RNA polymerase factor sigma-54; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.784
oatA
Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.758
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.732
eep_1
Metalloprotease RseP; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.726
AOM16887.1
Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.687
AOM17257.1
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.648
AOM17288.1
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.648
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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