Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
copY_2Penicillinase repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)    
Predicted Functional Partners:
copZ
Copper-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.986
copB_2
Copper-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.949
copA_2
ATPase P; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.930
CzcD
Cobalt transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.731
cutC_3
Copper homeostasis protein CutC; Participates in the control of copper homeostasis. Belongs to the CutC family.
      
 0.719
MntH
Manganese transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.601
AOM16705.1
Copper resistance protein CopZ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.600
AOM15280.1
Topology modulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.571
StbD
Prevent-host-death protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.559
perR
Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family.
     
 0.559
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
Server load: low (6%) [HD]