Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AOM15474.1Ribosomal silencing factor RsfS; Derived by automated computational analysis using gene prediction method: Protein Homology. (107 aa)    
Predicted Functional Partners:
nadD
Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
  
 0.982
AOM15475.1
SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.972
AOM17577.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.958
yqeH
GTPase; In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.953
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
  0.937
rpmH
50S ribosomal protein L34; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL34 family.
   
 
 0.925
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
  
 0.924
yhbY
RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.912
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
  0.910
rplQ
50S ribosomal protein L17; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.905
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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