Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
arlSHistidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)    
Predicted Functional Partners:
arlR_2
PhoB family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.998
srrA_2
PhoB family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.845
srrA_1
PhoP family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.835
vicR
PhoP family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.831
phoP_3
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.818
AOM14786.1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.758
gnd_1
6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
       0.746
hssR_2
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.743
AOM17140.1
XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.742
CiaR
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.728
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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