Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ulaGAscorbate 6-phosphate lactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)    
Predicted Functional Partners:
AOM15512.1
PTS ascorbate transporter subunit IIC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.996
ulaD
Catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.996
AOM15511.1
PTS ascorbate transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.995
SgaB
PTS ascorbate transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.995
AOM16668.1
PTS ascorbate transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.937
ulaA_2
Glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.926
SgbU
Xylulose 5-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.915
AOM15844.1
PTS lactose transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.910
ulaB
PTS ascorbate transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.910
AOM15509.1
DeoR faimly transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.837
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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