Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
msrAMethionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (172 aa)    
Predicted Functional Partners:
msrB
Methionine sulfoxide reductase B; This stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.995
msrC
GAF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.819
TetL
Tetracycline resistance protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.806
yozE
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0346 family.
       0.799
AOM15605.1
Lipase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.747
AOM15606.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.747
mecA
Competence negative regulator MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
     
 0.669
aacA-aphD
2-aminoglycoside phosphotransferase; Involved in resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region. The C-terminal region is a kinase that phosphorylates several 4,6-disubstituted aminoglycosides.
     
 0.629
nrdH
Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.533
AOM15604.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.503
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.