Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AOM15666.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)    
Predicted Functional Partners:
lytG
N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.907
AOM17587.1
Peptidase M15; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.854
AOM15664.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.746
afr
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.592
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
     
 0.564
ygfU
Uric acid permease PucJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.559
NifJ
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.508
phnW
2-aminoethylphosphonate:pyruvate aminotransferase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
  
 0.464
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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