Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ydcRGntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)    
Predicted Functional Partners:
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
      0.721
guaC
Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
       0.691
NifJ
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.566
Pgm2
Phosphoglucomutase; Catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.559
yxaF
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.507
AOM16628.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.507
AOM15857.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.506
AcrR2
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.506
AOM17238.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.506
AOM17445.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.506
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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