| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ComEB | ComEC | AL014_05395 | AL014_05400 | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.959 |
| ComEB | Dut | AL014_05395 | AL014_13230 | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.944 |
| ComEB | HolA | AL014_05395 | AL014_05405 | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.832 |
| ComEB | NifJ | AL014_05395 | AL014_07265 | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.654 |
| ComEB | cmk | AL014_05395 | AL014_04715 | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.903 |
| ComEB | comEA_1 | AL014_05395 | AL014_05380 | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Competence protein ComEA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.836 |
| ComEB | dnaG | AL014_05395 | AL014_04625 | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.779 |
| ComEB | tdk_1 | AL014_05395 | AL014_14960 | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidine kinase; Catalyzes the formation of thymidine 5'-phosphate from thymidine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.933 |
| ComEB | thyA | AL014_05395 | AL014_04785 | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.938 |
| ComEB | tmk | AL014_05395 | AL014_08670 | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.980 |
| ComEC | ComEB | AL014_05400 | AL014_05395 | Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.959 |
| ComEC | HolA | AL014_05400 | AL014_05405 | Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.942 |
| ComEC | NifJ | AL014_05400 | AL014_07265 | Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.654 |
| ComEC | comEA_1 | AL014_05400 | AL014_05380 | Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Competence protein ComEA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.977 |
| Dut | ComEB | AL014_13230 | AL014_05395 | dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.944 |
| Dut | tdk_1 | AL014_13230 | AL014_14960 | dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Thymidine kinase; Catalyzes the formation of thymidine 5'-phosphate from thymidine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.962 |
| Dut | thyA | AL014_13230 | AL014_04785 | dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.964 |
| Dut | tmk | AL014_13230 | AL014_08670 | dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.941 |
| HolA | ComEB | AL014_05405 | AL014_05395 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.832 |
| HolA | ComEC | AL014_05405 | AL014_05400 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.942 |
STRING v12.5 is now available!
