Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AOM15754.1Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)    
Predicted Functional Partners:
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
 
  
 0.951
murI_1
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
       0.859
ykuL
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.708
frmB_2
Tributyrin esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.653
AOM16762.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.538
artQ
Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.506
ahpC
Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
   
 
 0.494
GlnC
Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.485
DinF
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.485
recJ
Recombinase RecJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.471
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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