Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CiaRTranscriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)    
Predicted Functional Partners:
vicK
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
AOM16757.1
Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.976
phoR_5
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.864
AOM17141.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.839
phoR_2
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.801
graS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.764
arlS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.728
walK
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.710
AOM14785.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.641
PspC
PspC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.620
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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