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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nupCPyrimidine nucleoside transporter NupC; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)    
Predicted Functional Partners:
deoA
Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.880
yfbR
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.784
ygfU
Uric acid permease PucJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.656
RihB
Nucleoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.639
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
  
  
 0.617
KdpA
Guanylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.580
AOM14835.1
Ribokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.506
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
  
 0.494
AOM15882.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.446
RbsR
LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.409
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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