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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GadC2Glutamate:gamma-aminobutyrate antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)    
Predicted Functional Partners:
gadC_3
Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.927
AOM16684.1
Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.927
glsA
Glutaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaminase family.
  
 0.843
amt
Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.702
pheDC
Decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.576
tdc
Decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine. Plays a role in acid resistance since tyramine production via tyrosine decarboxylation appears to provide a cytosolic pH maintenance mechanism that helps the bacterium cope with acid stress such as that encountered in gastrointestinal tract (GIT) environments. Therefore, may contribute to the colonization of the human GIT by E.faecium (By similarity).
 
  
 0.566
treB
PTS maltose transporter subunit IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.529
AOM14759.1
Sugar phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.447
AOM17561.1
Oligo-1,6-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.447
MalA
Oligo-1,6-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.447
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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