Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PphASerine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)    
Predicted Functional Partners:
AOM17347.1
Snf2 family helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.722
AOM17615.1
Replication protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.712
rep_1
Replication protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.712
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.671
AOM16015.1
Sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0176 family.
 
     0.644
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 
 0.608
Tex
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.601
groEL
Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.590
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.572
GloA
Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
   0.524
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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