Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ldcAPeptidase S66; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)    
Predicted Functional Partners:
proX_2
prolyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.658
AOM17587.1
Peptidase M15; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.651
fetB
Iron ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.631
csd_4
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.615
murC
UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
    
 0.610
cwlC
Cell wall hydrolase; Probably involved in cell-wall metabolism. Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.
    
 0.567
walK-2
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.566
AOM17248.1
N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.559
vicR
PhoP family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.559
AOM17408.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.559
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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