STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lytA_2N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)    
Predicted Functional Partners:
Hol
Holin; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.775
AOM16210.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
manZ_3
PTS mannose family transporter subunit IID; Hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.765
algB
Transcription antiterminator BglG; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.765
AOM16211.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.655
AOM16212.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.655
manY_2
PTS mannose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.566
purQ
Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...]
      
 0.564
AOM16216.1
Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.548
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family.
      
 0.530
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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