Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AOM16244.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)    
Predicted Functional Partners:
AOM16243.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.789
AOM16245.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.785
AOM16246.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
AOM16242.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.762
mprF-2
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
  
     0.648
AOM16247.1
Antirepressor; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.549
AOM16018.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.525
AOM15588.1
Peptidoglycan-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.520
yopX_2
DNA-packaging protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.486
AOM17377.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.476
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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