close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xerC_6Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family. (400 aa)    
Predicted Functional Partners:
AOM14771.1
Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.735
AOM16361.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.616
ArdA
Antirestriction protein ArdA; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.602
AOM17612.1
Replication initiation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.591
xerC_5
Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family.
  
     0.589
xerS
Recombinase XerS; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family.
   
  
 0.585
AdrA
Antirestriction protein ArdA; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.569
xerD
Recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
  
    0.526
AOM16488.1
Glucosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.524
AOM14977.1
Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.517
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.