close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOM16376.1Cro/Cl family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)    
Predicted Functional Partners:
potA
Spermidine/putrescine ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
  
 0.874
PotD
Spermidine/putrescine ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.830
PotB
Spermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.818
AOM16377.1
NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.803
potC_1
Spermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.796
Coab
DNA/pantothenate metabolism flavoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.695
yfaY
Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
     
 0.679
AOM15277.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.579
coaC
Decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.490
AOM15864.1
acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.471
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
Server load: low (34%) [HD]