Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AdaCysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (154 aa)    
Predicted Functional Partners:
queG
Epoxyqueuosine reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.915
yutF
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.560
yfkN
5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family.
       0.559
yutD
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.559
AOM17540.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.559
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.558
AOM15074.1
DNA-entry nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.553
AOM16488.1
Glucosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.518
AOM15430.1
Iron-sulfur cluster biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.486
NifJ
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.485
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.