close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOM16488.1Glucosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)    
Predicted Functional Partners:
cadA
Cadmium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.769
yfhO
Copper ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.722
vraS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.674
ktrA
Potassium transporter Trk; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.671
vraR_2
LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.668
AOM15426.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.654
AOM15430.1
Iron-sulfur cluster biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.654
GtrA
Teichoic acid glycosylation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.553
Ada
Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
     
 0.525
xerC_6
Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family.
      
 0.524
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
Server load: low (32%) [HD]