Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
arcDAmino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)    
Predicted Functional Partners:
arcA
Arginine deiminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.956
ArcT
Aminotransferase; Associated with arginine deiminase pathway genes; probably functions in arginine catabolism; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.912
arcB
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
  
 0.883
arcC
Carbamate kinase; Catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.816
Crp
Cyclic nucleotide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.559
argR2
ArgR family transcriptional regulator; Regulates arginine biosynthesis genes.
      
 0.534
argR-2
ArgR family transcriptional regulator; Regulates arginine biosynthesis genes.
     
 0.523
peb1A
Glutamine ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.470
mnmA
Thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
  
    0.432
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
Server load: low (10%) [HD]