STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtnN5'-methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (230 aa)    
Predicted Functional Partners:
luxS
S-ribosylhomocysteinase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
 
 
 0.985
nudF
ADP-ribose pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.904
AOM16506.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.881
yecD_3
Isochorismatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.809
cysK
Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
  
 0.573
FeuA
Ferrichrome ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.573
cysM_4
Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.573
AOM15134.1
Succinyl-diaminopimelate desuccinylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.571
PepV2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.571
iscS
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.566
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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