close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BglHaryl-phospho-beta-D-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 1 family. (498 aa)    
Predicted Functional Partners:
MalA
Oligo-1,6-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.974
PtsG2
Sugar permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.936
glcK
Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.910
crr
Sugar permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.907
pgi
Glucose-6-phosphate isomerase; Functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family.
     
 0.904
Pgm2
Phosphoglucomutase; Catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
dexB_1
Glucan 1,6-alpha-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.874
licB_1
PTS cellobiose transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.770
licB_2
PTS cellobiose transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.770
licB_3
PTS cellobiose transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.770
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.