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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOM16723.1GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)    
Predicted Functional Partners:
PhnX
Phosphonoacetaldehyde hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.567
AOM16724.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.527
phnX
Phosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family.
 
    0.447
Pbp5
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.432
AOM16722.1
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.426
YkgC
Pyridine nucleotide-disulfide oxidoreductase; Involved in disulfide oxidoreductase activity and electron transport; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.412
phnW
2-aminoethylphosphonate:pyruvate aminotransferase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
  
     0.401
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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