Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
pepVDipeptidase PepV; Divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; Derived by automated computational analysis using gene prediction method: Protein Homology. (472 aa)    
Predicted Functional Partners:
pepQ
Peptidase M24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M24B family.
 
 
 0.896
pepT
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
  
  
 0.877
pepF
Oligopeptidase PepB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.871
pepO
Peptidase M13; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.867
nnrD
Carbohydrate kinase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
       0.777
pepC
Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase C1 family.
   
  
 0.688
pepS
Peptidase M29; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.609
pcp
Pyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.
      
 0.560
dtpT
Peptide transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.550
AOM16769.1
acyl-CoA thioester hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.535
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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