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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ndoAPemK family transcriptional regulator; Toxic component of a type II toxin-antitoxin (TA) system. (120 aa)    
Predicted Functional Partners:
Alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
     
 0.912
acpS
4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
     
 0.885
mazF
PemK family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.841
relE
Addiction module toxin RelE; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.787
AOM16528.1
AbrB family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.725
cshA-2
DEAD/DEAH box helicase; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily.
     
 0.599
cdr_2
CoA-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.571
rpsR
30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
      
 0.456
yybR
HxlR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.436
ytcD
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.436
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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