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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DinFDiguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)    
Predicted Functional Partners:
recX_1
Recombinase RecX; Modulates RecA activity; Belongs to the RecX family.
     
 0.795
yfaY
Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
 
   
 0.705
rpsA
30S ribosomal protein S1; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.601
AOM17525.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.589
AOM16826.1
GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.587
gap
Glyceraldehyde-3-phosphate dehydrogenase; NAD-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
  
 0.542
GapA
Glyceraldehyde-3-phosphate dehydrogenase; NAD-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
  
 0.542
AOM15754.1
Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.520
AOM16019.1
Phosphoglycolate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.434
macB_5
Sulfate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.426
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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