Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kup_2Potassium transporter Kup; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family. (663 aa)    
Predicted Functional Partners:
amt
Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.858
disA
Hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
      
 0.753
nrnA_2
Oligoribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.687
AOM16828.1
Hemolysin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.651
cfiB
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
      
 0.568
AOM16830.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.546
mscL
Mechanosensitive ion channel protein MscL; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
  
   
 0.482
pnuC_1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.480
ktrA
Potassium transporter Trk; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.452
mscS
Mechanosensitive ion channel protein MscS; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.442
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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