Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lrgA_1Murein hydrolase transporter LrgA; Derived by automated computational analysis using gene prediction method: Protein Homology. (136 aa)    
Predicted Functional Partners:
yohK
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.997
AOM16865.1
M protein trans-acting positive regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.607
fabG_2
3-ketoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.578
metG_1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.561
sdhC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.460
AOM16492.1
Multidrug transporter; Confers resistance to fosfomycin and deoxycholate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.460
NifJ
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.428
codY
Transcriptional repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
      
 0.401
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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