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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOM16897.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (120 aa)    
Predicted Functional Partners:
yloV_2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.989
rpmB
50S ribosomal protein L28; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL28 family.
       0.796
recG
ATP-dependent DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
       0.789
CsbD
General stress protein CsbD; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0337 (CsbD) family.
     
 0.747
AOM15604.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.684
AOM15872.1
Fatty acid-binding protein DegV; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.672
plsX
Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
 
   
 0.660
AOM15318.1
DNA-binding protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
 
   
 0.596
AOM15290.1
AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.564
whiA
Sporulation regulator WhiA; Involved in cell division and chromosome segregation.
  
     0.560
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.