Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pppAPeptidase A24; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)    
Predicted Functional Partners:
comGA
Secretion system protein E; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.970
epsF
Secretion system protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.951
ComGF
Competence protein ComGF; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.905
comGC
Competence protein ComG; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.894
ComEC
Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.872
dps
Ferritin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Dps family.
     
 0.787
dprA
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.768
comEA_1
Competence protein ComEA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.750
ComFA
DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.670
xylB
Gluconate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FGGY kinase family.
       0.619
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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