Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
pepF1Oligoendopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (601 aa)    
Predicted Functional Partners:
pepA
Glutamyl aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.826
AOM17220.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.781
pepO
Peptidase M13; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.617
pepS
Peptidase M29; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.570
ypwA
Carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.
 
    0.498
AOM17218.1
Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.497
pepV
Dipeptidase PepV; Divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.470
pepT
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
   
  
 0.434
AOM17221.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.434
purB
Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
    0.426
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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