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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
frmB_2Tributyrin esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)    
Predicted Functional Partners:
AOM15274.1
GDSL family lipase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.849
bmr3_2
Multidrug MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.839
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
       0.771
SagA
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.749
AOM15547.1
Phospholipase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.670
frmR_1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.623
AOM15605.1
Lipase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.577
AOM17290.1
Rhamnogalacturonan acetylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.573
iadA
Isoaspartyl dipeptidase; Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation. Belongs to the peptidase M38 family.
     
 0.565
thiN
Thiamine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.498
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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