Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pbp2APenicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (723 aa)    
Predicted Functional Partners:
Pbp2B
Cell division protein FtsI; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.994
Pbp5
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.989
PbpA
Cell division protein FtsI; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.971
Pbp1B
Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
0.947
DacA
D-alanyl-D-alanine carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family.
  
 
 0.934
ponA
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
0.927
FtsW
Cell division protein FtsW; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family.
 
 
 
 0.913
AOM17587.1
Peptidase M15; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.907
ftsW_1
Cell division protein FtsW; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family.
 
 
 
 0.907
mecA
Competence negative regulator MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
  
   
 0.853
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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