Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cypCCytochrome; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
    
 0.923
AOM15507.1
Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.779
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.771
dltA
Alanine-phosphoribitol ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent A [...]
  
 
 0.770
ysnF
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.730
bcrC
Phospholipid phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.670
Fdh
Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.643
ydbD
Manganese catalase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.639
AOM16518.1
Phosphoesterase PA-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.623
sbcC
Exonuclease SbcC; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.601
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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