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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recDExodeoxyribonuclease V subunit alpha; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (862 aa)    
Predicted Functional Partners:
gpmA_4
Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.883
trmL
RNA methyltransferase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
       0.838
AOM17181.1
Zinc protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.826
YueF
M16 family metallopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.784
TerL
Terminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.729
addA
DNA helicase UvrD; ATP-dependent DNA helicase.
  
 
 0.710
rlmA
50S rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.708
recJ
Recombinase RecJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.686
dnaN
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.663
PmrA
Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.581
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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