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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOM17366.1LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)    
Predicted Functional Partners:
desK
ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.985
vraS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.928
sagG_3
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.837
AOM17370.1
Antibiotic ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.826
AOM17369.1
Antibiotic ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.823
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
      
 0.769
sapB
Magnesium transporter MgtC; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.565
AOM14785.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.537
graS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.524
phoR_5
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.521
Your Current Organism:
Enterococcus faecium
NCBI taxonomy Id: 1352
Other names: ATCC 19434, CCUG 542, CFBP 4248, CIP 103014, DSM 20477, E. faecium, JCM 5804, JCM 8727, LMG 11423, LMG:11423, NBRC 100485, NBRC 100486, NCDO 942, NCIMB 11508, NCTC 7171, Streptococcus faecium
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