STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EWM64_g10785Uncharacterized protein. (328 aa)    
Predicted Functional Partners:
SUS1
Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...]
    
 0.696
EWM64_g10098
SCA7 domain-containing protein.
    
 0.669
EWM64_g10973
Uncharacterized protein.
    
 0.664
EWM64_g3114
TFIID_20kDa domain-containing protein.
    
 0.655
EWM64_g5199
Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...]
    
  0.650
EWM64_g4140
TAF domain-containing protein.
    
  0.638
EWM64_g1676
WD_REPEATS_REGION domain-containing protein.
    
  0.638
EWM64_g7883
Uncharacterized protein.
    
  0.611
EWM64_g5197
Uncharacterized protein.
    
  0.611
EWM64_g1299
FAT domain-containing protein; Belongs to the PI3/PI4-kinase family.
    
 0.609
Your Current Organism:
Hericium alpestre
NCBI taxonomy Id: 135208
Other names: H. alpestre
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.