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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMG48652.1Histidinol phosphate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PHP hydrolase family. HisK subfamily. (262 aa)    
Predicted Functional Partners:
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 
 0.949
AMG48378.1
Histidinol phosphate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PHP hydrolase family. HisK subfamily.
  
  
 
0.922
hisC
Histidinol-phosphate aminotransferase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.921
AMG48413.1
Histidinol phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PHP hydrolase family. HisK subfamily.
     
  0.900
hisI
Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.688
AMG49210.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.656
hisB
Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.603
AMG48651.1
AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.602
AMG49529.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.532
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.507
Your Current Organism:
Enterococcus gallinarum
NCBI taxonomy Id: 1353
Other names: ATCC 49573, CCUG 18658, CECT 970, CIP 103013, DSM 24841, E. gallinarum, JCM 8728, LMG 13129, LMG:13129, NBRC 100675, NCDO 2313, NCIMB 702313, NCTC 12359, Streptococcus gallinarum, strain F87/276, strain PB21
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